Hi Nick, so if that IE reset thing does not do the trick, then try this - download the ProcDump utility from here:
http://technet.microsoft.com/en-us/sysinternals/dd996900.aspx

Unzip that and then open up a command window and cd to that directory.

Then start up MoI, wait until approximately halfway through the long startup process and then type in the following in the command window: procdump moi

That will capture a snapshot of MoI's current program state as a crash dump file named MoI.dmp, and if you send that to me in e-mail to moi@moi3d.com I might be able to see what is going on during that long startup period.

- Michael