Thanks for the reply! I've tried to isolate a reproducible problem and think I've found it. Whenever I minimize the program, my mac desktop / finder crashes and sends me to the login screen. When I log back in, the program won't run until I kill the wineskin processes. A full reboot also allows the program to run until I attempt to minimize it again.

Hi Ryan, do you possibly see any different behavior if you change the operating system setting as described here? :
http://moi3d.com/forum/index.php?webtag=MOI&msg=6866.2

- Michael

Michael,

I do have a three-monitor setup using HDMI, DisplayPort and StarTech USB32DVIPRO. I turned off the separate spaces feature on OSX and rebooted my machine. The issue persisted when I attempted to minimize the MOI application. Thanks for the followup again!