VR and AR is a dramatically better experience for 3D content creators, and will certainly win out in the long haul. That said, the current offering for VR 3D creation is limited relative to its windowed 3D predecessors, but development is happening rapidly, the cost of gear has been cut in half, and people are adopting in droves.
Watch out! VR CAD is coming for us all, and I couldn't be happier about it.. :)
Keith and Chip, retopo can be a pain indeed, but I often get quite good results in ZBrush using ZRemesher with a low poly count and low adaptive size, then perform a Project All, subdivide, Project All again, and so on.
Routb3D and PaQ, I already got RSI from a Wacom Cintiq (sold it again after half a year), so I'm afraid VR creation is not the way to go for me personally. I do love the immersive 360 degrees 3D experience though.