The wires on the sides play the role of shrouds on a boat!
They prevent the top piece from falling from one side or the other!
You can understand it better if you imagine this!
The wire becomes "solid"! The side shrouds become useless!
It is the bottom piece that "holds" the top piece!
I made a suggestion to Meshlab to add an option to reverse the wheel mouse direction. They accepted it and it is in version 2020.07. https://www.meshlab.net/