An interesting recent blog article on this very subject:

14 Cloud Software Myths Debunked for Manufacturing Software

http://blog.cnccookbook.com/2015/03/10/14-cloud-industrial-software-myths-debunked/

An excerpt:
Consider that OnShape has raised $64M in Venture Capital from some top firms. Those guys don’t invest that kind of money unless they smell a huge success in the offing. They are literally betting this company can change the whole face of CAD and garner a big share of that market.

Ed Ferguson