As much as I love the wacom and drawing with my hand, the mouse still is my number one choice for most 3d work, mainly because it's accurate, hand-twitch free, and uses less work on the hand. With Zbrush I love using my bamboo create, but their are times where I like the mouse better. One thing I'll say is this, touching little icons with your fingers can be a real pain in the you know what! As far as the prices though, oh gosh, they seriously need some competition in the market, the cintiq 22 probably cost them $1500 to produce, but at least you know it's good quality, oh and no pen nibs! (: