Also it's possible if your system registry gets a bit mangled that IE itself gets confused about how to handle permissions for scripting stuff.

If that's the problem then that can be fixed by doing a reset of IE settings. There's a reset button under the system Control Panel > Internet Options > Advanced tab as shown in this blog post:
http://blogs.msdn.com/ie/archive/2006/06/12/628499.aspx

That might fix it up.

- Michael