Hi Brian, here is one idea using sweep.

To start with, I drew a path like this:



Then I drew a second curve that generally follows along that path, but kind of goes in bumps along it:



Here is a closeup so you can see more how this second curve is shaped:



That second curve should extend all the way past the ends of the original.

Now you can select the circle, run Construct / Sweep to build this tube:



Then while still inside of the Sweep command, click the "Pick scaling rail" button and pick the lumpy curve as the scaling rail. Also uncheck the option for "maintain height".

That will build a kind of lumpy tube like this:





Now use that as a base shape and take it into 3D coat and paint some kinds of small ripples and fold looking kind of textures on it.

Not sure if that helps you or not, but that might be a good way to try...

- Michael