Spirit of the Guide Helper Lines is to work with only the Function called! ;)

Call any function
Click without relase, move, release

---can be make before the first click of the function, after the first click of the function, before the last click of the function---

Don't forget that you can press 1 second on the little "white mark" for have more functions of the Helper Line itself
(Right or Left click)

Move - Re Orient - Rotate - Division Snap - Projection Next Point

Of course you can use the plugin for persistant Guide Lines but no need with some training! ;)