Hello Brian.

@You: "My question is does anyone have any thoughts on potential problems of this workflow?"

Almost nothing. I work everyday with OneDrive on my PCs, iPadPro and my Android smartphones and I have almost no problem.

Only sometimes OneDrive needs a little bit more time to synchronize, but nothing else.

I use the OneDrive of 1TB boundled with my "Microsoft Office365 Personal" annual subscription.

Ciao.