Size, differentiation and readability are typical usability issues and not aesthetic problems. Even though I personally think that both terms overlap in meaning to some point (because attractiveness catalyzes the acceptance and therefore affects the usability) for clarity in such discussion I think they should not be mixed: 
 
Usability = ease of use 
Aesthetics = attractiveness 
 
And I totally agree with you – usability factors should never be sacrificed in favor of aesthetic factors. They should be supported by them. But again, a professional should know all that. 
 
/Aesthetics IMHO are always subjective.  
 
No this is just very popular delusion. Applied aesthetics and people working in that area study and employ the popular/group reaction to visual problems. Not the individual characteristics. 
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