FWIW, I've been running Moi3D on Ubuntu 20.04 under Wine since version 7 without incident. Currently running Moi3D V5 with Wine development version (9.1) which I've been doing for a few years as I found performance was better without any reliability problems. In the beginning I would thinker with moi.ini settings, but for quite some time have been running defaults as it just seems to work. The only very small nuisance is the "view controls window" which sometimes will stay in foreground of native Linux apps, but it is harmless. I would try restoring defaults in both Moi3D & Wine.

Sven